QKI

Across TCGA pan-cancer cohorts, QKI RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated QKI data layer compared with 7 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher QKI RNA is associated with better overall survival. In most high-consensus cancer types, elevated QKI expression acts as an unfavorable survival marker, although some lineages such as UCS and KIRC show a favorable association.

UCS, STAD, and BLCA are the cancer types where QKI RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Median	II,III,IV	0.720	0.255	<.001	116	view →
STAD	OS	Tertile	All	0.575	0.851	.001	86	view →
BLCA	DFS	Quartile	All	0.268	0.452	.003	53	view →
OV	OS	Tertile	III,IV	0.257	0.350	.009	34	view →
KIRC	OS	Tertile	All	0.730	0.572	.002	33	view →
SKCM	OS	Tertile	IV	0.823	0.249	.007	25	view →
ESCA	OS	Tertile	All	1.000	0.489	.008	24	view →
LIHC	OS	Quartile	All	0.669	0.812	.008	23	view →
THYM	DFS	Tertile	II,III,IV	1.000	0.525	.013	15	view →
COAD	OS	Tertile	IV	0.797	0.260	.011	12	view →
MESO	OS	Median	All	0.306	0.460	.016	12	view →
KICH	DFS	Tertile	II,III,IV	0.526	0.934	.018	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

QKI–UCS (OS)

Open the UCS breakdown →