QKI

Across TCGA patient cohorts, QKI mutation is significantly associated with the RNA expression of many other genes, with 5,877 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible QKI-associated genes across cancer lineages are RNA5SP412, RNU6-13P, and LINC00458. Each is linked with QKI in more than 2 cancer types. Because this analysis shows association rather than direction, both QKI-to-partner and partner-to-QKI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP412 grouped by QKI-low versus QKI-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QKI→partner) and Y-score (partner→QKI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP412 →	+0.405	+1.304	<.001	.007	3	3
UCEC	RNU6-13P →	+0.145	+1.559	.005	.001	3	3
UCEC	LINC00458 →	+0.119	+1.363	.002	<.001	3	3
ESCA	NATP →	+0.482	+3.394	<.001	.003	3	3
SKCM	RNU6-956P →	+0.944	+4.147	<.001	.008	3	3
HNSC	MIR6870 →	+0.901	+3.748	.002	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,877 associations by consensus.

RNA5SP412 by QKI expression — UCEC

Explore this box plot interactively →