QKI

Across TCGA cell cohorts, QKI RNA expression is significantly associated with the go_rna of many other GO terms, with 5,037 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible QKI-associated GO terms across cancer lineages are DNA-templated transcription initiation, Spliceosome-depend formation of circular RNA, and Positive regulation of cell cycle. Each is linked with QKI in more than 14 cancer types. Because this analysis shows association rather than direction, both QKI-to-partner and partner-to-QKI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by QKI-low versus QKI-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (QKI→partner) and Y-score (partner→QKI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DNA-templated transcription initiation →	+0.061	+1.269	<.001	<.001	3	15
BREAST	Spliceosome-depend formation of circular RNA →	+0.225	+1.709	<.001	<.001	3	15
SOFT_TISSUE	Positive regulation of cell cycle →	+0.070	+1.051	<.001	<.001	3	14
BREAST	Negative regulation of protein-containing complex disassembly →	+0.104	+2.080	<.001	<.001	3	14
BREAST	Regulation of chromosome segregation →	+0.117	+1.611	<.001	<.001	2	14
BLOOD_Lymphoma	Nucleocytoplasmic transport →	+0.078	+2.059	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,037 associations by consensus.

DNA-templated transcription initiation by QKI expression — SOFT_TISSUE

Explore this box plot interactively →