QKI

Across TCGA cell cohorts, QKI mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible QKI-associated genes across cancer lineages are UGT2B10, OR10Q1, and CD207. Each is linked with QKI in more than 1 cancer types. Because this analysis shows association rather than direction, both QKI-to-partner and partner-to-QKI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UGT2B10 grouped by QKI-low versus QKI-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QKI→partner) and Y-score (partner→QKI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	UGT2B10 →	+0.413	+5.000	<.001	.006	3	1
PANCREAS	OR10Q1 →	+0.033	+5.614	<.001	.002	3	1
BLOOD_Leukemia	CD207 →	+0.197	+2.938	<.001	.008	3	1
BLOOD_Leukemia	VSX2 →	+0.020	+3.580	.001	.001	3	1
BLOOD_Leukemia	KIAA0319 →	+0.160	+3.793	<.001	.001	3	1
BLOOD_Leukemia	HIPK4 →	+0.045	+3.359	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

UGT2B10 by QKI expression — PANCREAS

Explore this box plot interactively →