QDPR

Across TCGA patient cohorts, QDPR protein abundance is significantly associated with the RNA expression of many other genes, with 14,742 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible QDPR-associated genes across cancer lineages are ABCA8, N4BP2L1, and RAI2. Each is linked with QDPR in more than 6 cancer types. Because this analysis shows association rather than direction, both QDPR-to-partner and partner-to-QDPR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, QDPR versus ABCA8 in UCEC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (QDPR→partner) and Y-score (partner→QDPR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ABCA8 →	+1.224	+0.307	<.001	<.001	3	7
HNSC	N4BP2L1 →	+0.905	+0.395	<.001	<.001	3	7
BRCA	RAI2 →	+1.096	+0.449	<.001	<.001	3	6
CCRCC	ASPA →	+1.291	+0.251	<.001	<.001	3	6
LSCC	PEBP4 →	+2.018	+0.316	<.001	<.001	3	6
GBM	CCNF →	-0.581	-0.382	.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,742 associations by consensus.

QDPR vs ABCA8 — UCEC

Explore this scatter interactively →