PYY

Across TCGA cell cohorts, PYY RNA expression is significantly associated with the RNA expression of many other genes, with 1,494 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PYY-associated genes across cancer lineages are CD68, GON7, and FPR2. Each is linked with PYY in more than 2 cancer types. Because this analysis shows association rather than direction, both PYY-to-partner and partner-to-PYY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PYY versus CD68 in KIDNEY, with a Pearson correlation of 0.47.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PYY→partner) and Y-score (partner→PYY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	CD68 →	+2.053	+0.424	<.001	.004	3	3
LARGE_INTESTINE	GON7 →	-0.535	-0.042	.002	.002	3	2
UPPER_AERODIGESTIVE_TRACT	FPR2 →	+0.082	+0.157	.001	.001	3	2
LARGE_INTESTINE	SELP →	+0.246	+0.042	<.001	<.001	3	2
KIDNEY	GOLGA8S →	+0.265	+0.452	<.001	.004	3	2
LUNG_NSCLC_LUSC	FBXO27 →	+2.290	+0.060	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,494 associations by consensus.

PYY vs CD68 — KIDNEY

Explore this scatter interactively →