PYURF

Across TCGA patient cohorts, PYURF RNA expression is significantly associated with the go_rna of many other GO terms, with 7,149 significant associations in total. OV shows the largest number of these associations.

The most reproducible PYURF-associated GO terms across cancer lineages are [4Fe-4S] cluster assembly, [2Fe-2S] cluster assembly, and Mitochondrial respiratory chain complex assembly. Each is linked with PYURF in more than 21 cancer types. Because this analysis shows association rather than direction, both PYURF-to-partner and partner-to-PYURF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, [4Fe-4S] cluster assembly grouped by PYURF-low versus PYURF-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PYURF→partner) and Y-score (partner→PYURF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	[4Fe-4S] cluster assembly →	+0.080	+0.528	<.001	.002	3	22
DLBC	[2Fe-2S] cluster assembly →	+0.068	+0.669	.001	<.001	3	21
UVM	Mitochondrial respiratory chain complex assembly →	+0.037	+0.762	<.001	<.001	3	21
ESCA	CAMP biosynthetic process →	-0.048	-0.424	.001	<.001	2	21
LAML	Signal peptide processing →	+0.048	+0.595	<.001	<.001	3	19
THYM	Peptidyl-serine autophosphorylation →	-0.071	-0.430	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,149 associations by consensus.

[4Fe-4S] cluster assembly by PYURF expression — DLBC

Explore this box plot interactively →