PYURF

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, PYURF protein abundance is significantly associated with the RNA expression of many other genes, with 9,823 significant associations in total. COAD shows the largest number of these associations.

The most reproducible PYURF-associated genes across cancer lineages are BNIP3L, VASP, and CALU. Each is linked with PYURF in more than 4 cancer types. Because this analysis shows association rather than direction, both PYURF-to-partner and partner-to-PYURF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PYURF versus BNIP3L in BRCA, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PYURF→partner) and Y-score (partner→PYURF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCABNIP3L →-0.539-0.382.001.00235
OVVASP →-0.471-0.586.006.00135
BRCACALU →-0.589-0.449.002.00535
OVADAM8 →-0.980-0.620<.001<.00135
OVREEP3 →-0.601-0.588.001<.00135
UCECCHST15 →-1.098-0.436.002.00335
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,823 associations by consensus.

PYURF vs BNIP3L — BRCA

Per-sample scatter of PYURF vs BNIP3L in BRCA (Pearson r = -0.27).

Explore this scatter interactively →

Exploration