PYURF

Across TCGA cell cohorts, PYURF RNA expression is significantly associated with the go_rna of many other GO terms, with 3,856 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PYURF-associated GO terms across cancer lineages are CMP biosynthetic process, Protein neddylation, and Purine deoxyribonucleoside monophosphate biosynthetic process. Each is linked with PYURF in more than 10 cancer types. Because this analysis shows association rather than direction, both PYURF-to-partner and partner-to-PYURF results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMP biosynthetic process grouped by PYURF-low versus PYURF-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PYURF→partner) and Y-score (partner→PYURF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	CMP biosynthetic process →	+0.106	+0.672	.003	.003	3	11
BREAST	Protein neddylation →	+0.096	+0.549	<.001	<.001	3	9
KIDNEY	Purine deoxyribonucleoside monophosphate biosynthetic process →	+0.133	+0.669	.004	.003	3	8
KIDNEY	DAMP biosynthetic process →	+0.133	+0.669	.004	.003	3	8
URINARY_TRACT	Skin epidermis development →	-0.131	-0.843	.003	.001	2	9
PANCREAS	Nucleoside monophosphate biosynthetic process →	+0.097	+0.462	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,856 associations by consensus.

CMP biosynthetic process by PYURF expression — LUNG_SCLC

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