PYROXD1

Across TCGA patient cohorts, PYROXD1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,546 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible PYROXD1-associated genes across cancer lineages are GAPDH, TPI1, and PEX5. Each is linked with PYROXD1 in more than 3 cancer types. Because this analysis shows association rather than direction, both PYROXD1-to-partner and partner-to-PYROXD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PYROXD1 versus GAPDH in LUAD, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PYROXD1→partner) and Y-score (partner→PYROXD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GAPDH →	+0.635	+0.328	.001	.001	3	4
OV	TPI1 →	+0.610	+0.372	.006	.001	3	4
OV	PEX5 →	+0.569	+0.342	.004	.003	3	4
OV	ADIPOR2 →	+0.840	+0.410	.001	.003	3	4
LSCC	STRAP →	+0.453	+0.211	.001	.003	3	4
LUAD	MRPS35 →	+0.533	+0.258	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,546 associations by consensus.

PYROXD1 vs GAPDH — LUAD

Explore this scatter interactively →