PYGL

Across TCGA cell cohorts, PYGL RNA expression is significantly associated with the go_rna of many other GO terms, with 5,114 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PYGL-associated GO terms across cancer lineages are Indole-containing compound biosynthetic process, Monoacylglycerol catabolic process, and Negative regulation of GTPase activity. Each is linked with PYGL in more than 7 cancer types. Because this analysis shows association rather than direction, both PYGL-to-partner and partner-to-PYGL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Indole-containing compound biosynthetic process grouped by PYGL-low versus PYGL-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PYGL→partner) and Y-score (partner→PYGL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Indole-containing compound biosynthetic process →	-1.280	-2.855	<.001	<.001	3	8
BONE	Monoacylglycerol catabolic process →	-0.216	-3.021	.002	<.001	3	8
BLOOD_Lymphoma	Negative regulation of GTPase activity →	-0.097	-2.297	<.001	<.001	3	8
STOMACH	Establishment of RNA localization →	+0.096	+3.423	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Phosphatidylserine catabolic process →	-0.171	-0.837	.002	.002	3	8
BONE	Substrate adhesion-dependent cell spreading →	+0.168	+2.609	.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,114 associations by consensus.

Indole-containing compound biosynthetic process by PYGL expression — STOMACH

Explore this box plot interactively →