PYDC1

Across TCGA patient cohorts, PYDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,048 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible PYDC1-associated GO terms across cancer lineages are Apoptotic mitochondrial changes, Regulation of release of cytochrome c from mitochondria, and Nucleoside triphosphate metabolic process. Each is linked with PYDC1 in more than 14 cancer types. Because this analysis shows association rather than direction, both PYDC1-to-partner and partner-to-PYDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Apoptotic mitochondrial changes grouped by PYDC1-low versus PYDC1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PYDC1→partner) and Y-score (partner→PYDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Apoptotic mitochondrial changes →	+0.055	+0.236	<.001	<.001	3	15
STAD	Regulation of release of cytochrome c from mitochondria →	+0.078	+0.395	<.001	<.001	3	13
STAD	Nucleoside triphosphate metabolic process →	+0.062	+0.214	<.001	<.001	3	13
STAD	ATP synthesis coupled electron transport →	+0.092	+0.209	<.001	.006	2	14
STAD	Mitochondrial membrane organization →	+0.085	+0.329	<.001	<.001	3	13
STAD	Oxidative phosphorylation →	+0.100	+0.296	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,048 associations by consensus.

Apoptotic mitochondrial changes by PYDC1 expression — STAD

Explore this box plot interactively →