PYDC1

Across TCGA patient cohorts, PYDC1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,036 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PYDC1-associated genes across cancer lineages are RNU5E-4P, STAG2, and CALCA. Each is linked with PYDC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PYDC1-to-partner and partner-to-PYDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PYDC1 versus RNU5E-4P in OV, with a Pearson correlation of 0.95.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PYDC1→partner) and Y-score (partner→PYDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RNU5E-4P →	+1.020	+1.444	<.001	.001	3	2
OV	STAG2 →	+0.625	+1.444	.005	.001	3	1
OV	CALCA →	-0.155	-1.630	.001	.006	3	1
OV	NNT →	-0.639	-1.489	<.001	.001	3	1
OV	POLR3GL →	+0.465	+1.444	.007	.001	3	1
OV	NKX2-4 →	+0.105	+1.540	.002	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,036 associations by consensus.

PYDC1 vs RNU5E-4P — OV

Explore this scatter interactively →