PYDC1

Across TCGA cell cohorts, PYDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 635 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PYDC1-associated GO terms across cancer lineages are Regulation of atrial cardiac muscle cell membrane repolarization, Necroptotic process, and Cytoplasmic translation. Each is linked with PYDC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PYDC1-to-partner and partner-to-PYDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of atrial cardiac muscle cell membrane repolarization grouped by PYDC1-low versus PYDC1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PYDC1→partner) and Y-score (partner→PYDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of atrial cardiac muscle cell membrane repolarization →	-0.183	-0.258	<.001	.003	3	3
SOFT_TISSUE	Necroptotic process →	-0.052	-0.358	.009	.004	3	3
LUNG_SCLC	Cytoplasmic translation →	+0.061	+0.156	<.001	.008	3	3
BLOOD_Leukemia	Regulation of cell proliferation in midbrain →	-0.793	-0.167	<.001	.004	3	3
SOFT_TISSUE	Regulation of systemic arterial blood pressure mediated by a chemical signal →	-0.221	-0.269	<.001	.002	3	3
SOFT_TISSUE	Response to potassium ion →	-0.067	-0.306	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 635 associations by consensus.

Regulation of atrial cardiac muscle cell membrane repolarization by PYDC1 expression — SOFT_TISSUE

Explore this box plot interactively →