PXYLP1

Across TCGA patient cohorts, PXYLP1 mutation is significantly associated with the RNA expression of many other genes, with 3,286 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PXYLP1-associated genes across cancer lineages are RNA5SP198, SNORA74C-2, and OR56A3. Each is linked with PXYLP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PXYLP1-to-partner and partner-to-PXYLP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP198 grouped by PXYLP1-low versus PXYLP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PXYLP1→partner) and Y-score (partner→PXYLP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP198 →	+0.343	+2.773	<.001	.001	3	2
CESC	SNORA74C-2 →	+0.213	+3.760	<.001	.007	3	2
LUAD	OR56A3 →	+0.732	+3.252	.002	.009	3	2
LUAD	HSD3BP3 →	+0.356	+3.643	<.001	.008	3	2
LUAD	OR8Q1P →	+0.191	+3.572	.002	.007	3	2
LUAD	LINC02327 →	+0.565	+3.918	.003	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,286 associations by consensus.

RNA5SP198 by PXYLP1 expression — UCEC

Explore this box plot interactively →