PXDC1

Across TCGA patient cohorts, PXDC1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,477 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PXDC1-associated genes across cancer lineages are COL6A3, TIMP2, and CNRIP1. Each is linked with PXDC1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PXDC1-to-partner and partner-to-PXDC1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PXDC1 versus COL6A3 in BRCA, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PXDC1→partner) and Y-score (partner→PXDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COL6A3 →	+1.441	+0.496	<.001	<.001	3	7
UCEC	TIMP2 →	+1.100	+0.374	.003	.001	3	7
OV	CNRIP1 →	+0.787	+0.488	<.001	<.001	3	6
OV	TNFAIP6 →	+1.556	+0.524	<.001	<.001	3	6
OV	FBN1 →	+1.151	+0.419	.002	.002	3	6
PDAC	PRKG1 →	+0.652	+0.422	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,477 associations by consensus.

PXDC1 vs COL6A3 — BRCA

Explore this scatter interactively →