PXDC1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, PXDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,691 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PXDC1-associated GO terms across cancer lineages are Wound healing, Positive regulation of myoblast fusion, and Regulation of proteolysis. Each is linked with PXDC1 in more than 15 cancer types. Because this analysis shows association rather than direction, both PXDC1-to-partner and partner-to-PXDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Wound healing grouped by PXDC1-low versus PXDC1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PXDC1→partner) and Y-score (partner→PXDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEWound healing →+0.137+3.306<.001<.001316
BONEPositive regulation of myoblast fusion →+0.271+2.892<.001<.001314
BONERegulation of proteolysis →+0.124+2.842<.001<.001314
BONECoagulation →+0.141+3.498<.001<.001313
LIVERSubstrate adhesion-dependent cell spreading →+0.191+1.917.004.001313
BONEEstablishment of protein localization to membrane →+0.059+2.725<.001<.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,691 associations by consensus.

Wound healing by PXDC1 expression — BONE

Box plot of Wound healing in PXDC1-low vs PXDC1-high samples in BONE.

Explore this box plot interactively →

Exploration