PWWP3B

Across TCGA cell cohorts, PWWP3B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,501 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible PWWP3B-associated GO terms across cancer lineages are Chondroblast differentiation, Positive regulation of mRNA catabolic process, and RNA catabolic process. Each is linked with PWWP3B in more than 6 cancer types. Because this analysis shows association rather than direction, both PWWP3B-to-partner and partner-to-PWWP3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chondroblast differentiation grouped by PWWP3B-low versus PWWP3B-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PWWP3B→partner) and Y-score (partner→PWWP3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Chondroblast differentiation →	-0.941	-1.047	<.001	<.001	3	6
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mRNA catabolic process →	+0.046	+0.459	.004	.005	3	6
CNS	RNA catabolic process →	+0.032	+0.512	.001	.005	3	6
OESOPHAGUS	Calcium ion transmembrane transport →	-0.070	-1.263	<.001	.003	3	6
BONE	Protein-RNA complex organization →	+0.067	+1.023	.004	.003	3	6
SOFT_TISSUE	Gamma-aminobutyric acid signaling pathway →	-0.154	-0.800	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,501 associations by consensus.

Chondroblast differentiation by PWWP3B expression — SOFT_TISSUE

Explore this box plot interactively →