PWWP3A

Across TCGA cell cohorts, PWWP3A RNA expression is significantly associated with the RNA expression of many other genes, with 12,102 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible PWWP3A-associated genes across cancer lineages are TMEM259, SPPL2B, and ADAT3. Each is linked with PWWP3A in more than 17 cancer types. Because this analysis shows association rather than direction, both PWWP3A-to-partner and partner-to-PWWP3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PWWP3A versus TMEM259 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.60.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PWWP3A→partner) and Y-score (partner→PWWP3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	TMEM259 →	+1.367	+1.117	<.001	<.001	3	18
LARGE_INTESTINE	SPPL2B →	+1.722	+1.256	<.001	<.001	3	18
UPPER_AERODIGESTIVE_TRACT	ADAT3 →	+1.353	+1.170	<.001	<.001	3	17
OESOPHAGUS	CACTIN →	+1.050	+1.298	.005	<.001	2	18
BREAST	FZR1 →	+1.174	+1.257	<.001	<.001	3	17
LUNG_NSCLC_LUSC	C19orf25 →	+1.012	+0.984	.001	.002	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,102 associations by consensus.

PWWP3A vs TMEM259 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →