PWWP2A

Across TCGA cell cohorts, PWWP2A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,597 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PWWP2A-associated GO terms across cancer lineages are Regulation of mitotic cytokinetic process, Positive regulation of mitotic cytokinetic process, and Regulation of cytokinetic process. Each is linked with PWWP2A in more than 12 cancer types. Because this analysis shows association rather than direction, both PWWP2A-to-partner and partner-to-PWWP2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic cytokinetic process grouped by PWWP2A-low versus PWWP2A-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PWWP2A→partner) and Y-score (partner→PWWP2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of mitotic cytokinetic process →	+0.122	+0.482	.001	.003	3	13
LUNG_SCLC	Positive regulation of mitotic cytokinetic process →	+0.122	+0.482	.001	.003	3	13
LUNG_SCLC	Regulation of cytokinetic process →	+0.122	+0.482	.001	.003	3	13
LUNG_NSCLC_LUSC	Positive regulation of telomere maintenance →	+0.043	+0.493	.004	.004	3	13
STOMACH	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.082	+0.458	.001	<.001	3	12
STOMACH	Protein sumoylation →	+0.079	+0.495	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,597 associations by consensus.

Regulation of mitotic cytokinetic process by PWWP2A expression — LUNG_SCLC

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