PWRN4

Across TCGA patient cohorts, PWRN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,826 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PWRN4-associated GO terms across cancer lineages are Cytoskeleton-dependent intracellular transport, Methylation, and Establishment of protein localization to membrane. Each is linked with PWRN4 in more than 16 cancer types. Because this analysis shows association rather than direction, both PWRN4-to-partner and partner-to-PWRN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoskeleton-dependent intracellular transport grouped by PWRN4-low versus PWRN4-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PWRN4→partner) and Y-score (partner→PWRN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Cytoskeleton-dependent intracellular transport →	+0.080	+0.119	<.001	<.001	3	17
STAD	Methylation →	+0.092	+0.136	<.001	<.001	3	17
STAD	Establishment of protein localization to membrane →	+0.100	+0.109	<.001	<.001	3	16
STAD	Transport along microtubule →	+0.081	+0.129	<.001	<.001	3	16
STAD	Peptidyl-lysine modification →	+0.101	+0.126	<.001	<.001	3	16
STAD	Neuron projection extension →	+0.060	+0.115	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,826 associations by consensus.

Cytoskeleton-dependent intracellular transport by PWRN4 expression — STAD

Explore this box plot interactively →