PWRN3

Across TCGA patient cohorts, PWRN3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,727 significant associations in total. THCA shows the largest number of these associations.

The most reproducible PWRN3-associated GO terms across cancer lineages are Golgi vesicle transport, Vacuole organization, and Vacuolar transport. Each is linked with PWRN3 in more than 17 cancer types. Because this analysis shows association rather than direction, both PWRN3-to-partner and partner-to-PWRN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Golgi vesicle transport grouped by PWRN3-low versus PWRN3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PWRN3→partner) and Y-score (partner→PWRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Golgi vesicle transport →	+0.081	+0.088	<.001	<.001	3	18
STAD	Vacuole organization →	+0.077	+0.089	<.001	<.001	3	18
STAD	Vacuolar transport →	+0.075	+0.090	<.001	<.001	3	18
STAD	Cytosolic transport →	+0.071	+0.086	<.001	<.001	3	18
STAD	Protein-containing complex disassembly →	+0.068	+0.090	<.001	<.001	3	18
STAD	ERAD pathway →	+0.063	+0.071	<.001	.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,727 associations by consensus.

Golgi vesicle transport by PWRN3 expression — STAD

Explore this box plot interactively →