PVT1

Across TCGA patient cohorts, PVT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,132 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PVT1-associated proteins across cancer lineages are BOP1, WDR12, and NOP58. Each is linked with PVT1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PVT1-to-partner and partner-to-PVT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PVT1 versus BOP1 in GBM, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PVT1→partner) and Y-score (partner→PVT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BOP1 →	+0.383	+0.858	<.001	<.001	3	8
LSCC	WDR12 →	+0.371	+0.711	<.001	<.001	3	7
BRCA	NOP58 →	+0.305	+0.716	<.001	<.001	3	7
LUAD	TBL3 →	+0.243	+0.815	<.001	<.001	3	6
LSCC	WDR36 →	+0.280	+0.767	<.001	<.001	3	6
LSCC	WDR75 →	+0.337	+0.795	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,132 associations by consensus.

PVT1 vs BOP1 — GBM

Explore this scatter interactively →