Across TCGA patient cohorts, PVRIG RNA expression is significantly associated with the protein abundance of many other proteins, with 11,152 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PVRIG-associated proteins across cancer lineages are ZFR, ZBTB7A, and CASTOR2. Each is linked with PVRIG in more than 3 cancer types. Because this analysis shows association rather than direction, both PVRIG-to-partner and partner-to-PVRIG results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PVRIG→partner) and Y-score (partner→PVRIG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ZFR →	+0.225	+0.462	<.001	<.001	3	4
GBM	ZBTB7A →	-0.325	-0.670	<.001	<.001	3	4
BRCA	CASTOR2 →	+0.432	+0.348	<.001	<.001	3	4
LSCC	RCOR3 →	+0.335	+0.385	.003	.006	3	4
GBM	SART1 →	+0.210	+0.487	.003	.004	3	4
GBM	NFKB1 →	-0.288	-0.602	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,152 associations by consensus.

Exploration

PVRIG survival (RNA) · tumor vs normal (RNA) · all PVRIG data types