PUS7L

Across TCGA patient cohorts, PUS7L protein abundance is significantly associated with the RNA expression of many other genes, with 12,455 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PUS7L-associated genes across cancer lineages are GINS1, SNED1-AS1, and STMN2. Each is linked with PUS7L in more than 3 cancer types. Because this analysis shows association rather than direction, both PUS7L-to-partner and partner-to-PUS7L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PUS7L versus GINS1 in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PUS7L→partner) and Y-score (partner→PUS7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GINS1 →	+0.633	+0.229	<.001	<.001	3	4
HNSC	SNED1-AS1 →	-0.495	-0.294	.004	.003	3	3
GBM	STMN2 →	-1.886	-0.361	<.001	.003	3	3
LUAD	CDCA3 →	+0.831	+0.384	<.001	.001	3	3
UCEC	TROAP →	+1.055	+0.268	<.001	.002	3	3
UCEC	TICRR →	+0.516	+0.213	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,455 associations by consensus.

PUS7L vs GINS1 — UCEC

Explore this scatter interactively →