PUS7L

Across TCGA cell cohorts, PUS7L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,658 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PUS7L-associated GO terms across cancer lineages are DNA strand elongation, Regulation of centrosome duplication, and Positive regulation of centriole replication. Each is linked with PUS7L in more than 14 cancer types. Because this analysis shows association rather than direction, both PUS7L-to-partner and partner-to-PUS7L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA strand elongation grouped by PUS7L-low versus PUS7L-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PUS7L→partner) and Y-score (partner→PUS7L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DNA strand elongation →	+0.155	+0.816	<.001	<.001	3	15
OESOPHAGUS	Regulation of centrosome duplication →	+0.095	+0.916	.002	.006	3	14
BLOOD_Lymphoma	Positive regulation of centriole replication →	+0.090	+0.960	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.062	+0.664	<.001	<.001	3	14
OESOPHAGUS	Sister chromatid cohesion →	+0.144	+0.815	<.001	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Centriole replication →	+0.112	+1.045	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,658 associations by consensus.

DNA strand elongation by PUS7L expression — PANCREAS

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