PUS1

Across TCGA patient cohorts, PUS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,245 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PUS1-associated proteins across cancer lineages are SRSF9, HEATR1, and TBL3. Each is linked with PUS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both PUS1-to-partner and partner-to-PUS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PUS1 versus SRSF9 in LSCC, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PUS1→partner) and Y-score (partner→PUS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SRSF9 →	+0.442	+0.566	<.001	<.001	3	7
LSCC	HEATR1 →	+0.458	+0.712	<.001	<.001	3	7
BRCA	TBL3 →	+0.388	+0.599	<.001	<.001	3	7
BRCA	DDX47 →	+0.515	+0.654	<.001	<.001	3	7
OV	NAA25 →	+0.348	+0.539	<.001	<.001	3	7
BRCA	NAT10 →	+0.493	+0.566	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,245 associations by consensus.

PUS1 vs SRSF9 — LSCC

Explore this scatter interactively →