Across TCGA cell cohorts, PURA RNA expression is significantly associated with the go_rna of many other GO terms, with 4,836 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PURA-associated GO terms across cancer lineages are Dendritic transport of messenger ribonucleoprotein complex, Endosomal transport, and Regulation of hippo signaling. Each is linked with PURA in more than 19 cancer types. Because this analysis shows association rather than direction, both PURA-to-partner and partner-to-PURA results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PURA→partner) and Y-score (partner→PURA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Dendritic transport of messenger ribonucleoprotein complex →	-0.076	-0.832	<.001	<.001	3	20
BONE	Endosomal transport →	+0.070	+0.800	.002	<.001	3	15
BONE	Regulation of hippo signaling →	+0.090	+0.815	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Negative regulation of hippo signaling →	+0.096	+0.773	<.001	.001	3	15
UPPER_AERODIGESTIVE_TRACT	Cytosolic transport →	+0.085	+1.057	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Negative regulation of cilium assembly →	+0.073	+0.757	.001	.002	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,836 associations by consensus.

Exploration

PURA survival (RNA) · tumor vs normal (RNA) · all PURA data types