PUM3

Across TCGA patient cohorts, PUM3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,909 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible PUM3-associated proteins across cancer lineages are UHRF2, CDC37L1, and NCAPH. Each is linked with PUM3 in more than 6 cancer types. Because this analysis shows association rather than direction, both PUM3-to-partner and partner-to-PUM3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PUM3 versus UHRF2 in LSCC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PUM3→partner) and Y-score (partner→PUM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	UHRF2 →	+0.427	+0.687	<.001	<.001	3	7
LSCC	CDC37L1 →	+0.371	+0.780	<.001	<.001	3	7
COAD	NCAPH →	+0.531	+0.496	.002	<.001	3	7
GBM	RANBP6 →	+0.358	+0.489	<.001	<.001	3	6
LUAD	NCAPG →	+0.456	+0.473	<.001	<.001	3	6
BRCA	PSIP1 →	+0.571	+0.858	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,909 associations by consensus.

PUM3 vs UHRF2 — LSCC

Explore this scatter interactively →