PUM2

Across TCGA patient cohorts, PUM2 protein abundance is significantly associated with the RNA expression of many other genes, with 19,257 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PUM2-associated genes across cancer lineages are CEBPZ, MASTL, and POLR1B. Each is linked with PUM2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PUM2-to-partner and partner-to-PUM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PUM2 versus CEBPZ in HNSC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PUM2→partner) and Y-score (partner→PUM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CEBPZ →	+0.892	+0.232	<.001	<.001	3	6
HNSC	MASTL →	+0.743	+0.219	<.001	<.001	3	6
LSCC	POLR1B →	+0.639	+0.258	<.001	<.001	3	6
LSCC	WDR43 →	+0.767	+0.290	<.001	<.001	3	6
LSCC	E2F6 →	+0.813	+0.328	<.001	<.001	3	6
GBM	GEN1 →	+0.743	+0.207	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,257 associations by consensus.

PUM2 vs CEBPZ — HNSC

Explore this scatter interactively →