PUDPP1

Across TCGA patient cohorts, PUDPP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,363 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible PUDPP1-associated GO terms across cancer lineages are Cardiac muscle cell differentiation, Regulation of intracellular steroid hormone receptor signaling pathway, and Oligodendrocyte differentiation. Each is linked with PUDPP1 in more than 5 cancer types. Because this analysis shows association rather than direction, both PUDPP1-to-partner and partner-to-PUDPP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cardiac muscle cell differentiation grouped by PUDPP1-low versus PUDPP1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PUDPP1→partner) and Y-score (partner→PUDPP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Cardiac muscle cell differentiation →	+0.050	+0.058	<.001	.001	3	5
ESCA	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.082	+0.064	<.001	.003	3	5
ESCA	Oligodendrocyte differentiation →	+0.057	+0.053	<.001	.006	2	6
ESCA	Insulin receptor signaling pathway →	+0.072	+0.049	<.001	.002	3	5
ESCA	Positive regulation of growth →	+0.051	+0.045	<.001	.005	3	5
ESCA	Obsolete ncRNA transcription →	+0.074	+0.072	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,363 associations by consensus.

Cardiac muscle cell differentiation by PUDPP1 expression — ESCA

Explore this box plot interactively →