PUDPP1

Across TCGA pan-cancer cohorts, PUDPP1 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated PUDPP1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher PUDPP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated PUDPP1 expression acts as an unfavorable survival marker.

KIRC, SKCM, and OV are the cancer types where PUDPP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.484	0.666	.016	36	view →
SKCM	DFS	Tertile	III,IV	0.141	0.618	.001	24	view →
OV	OS	Tertile	IV	0.170	0.758	.044	18	view →
PAAD	DFS	Tertile	II,III,IV	0.256	0.458	.029	18	view →
KIRP	OS	Tertile	II,III,IV	0.216	0.771	.049	9	view →
GBM	OS	Tertile	All	0.185	0.279	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

PUDPP1–KIRC (OS)

Open the KIRC breakdown →