PTTG1IP

Across TCGA pan-cancer cohorts, PTTG1IP mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated PTTG1IP data layer compared with 26 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher PTTG1IP mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated PTTG1IP expression acts as an unfavorable survival marker.

COAD, PDAC, and CCRCC are the cancer types where PTTG1IP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.906	1.000	.007	66	view →
PDAC	OS	Median	III,IV	0.639	0.870	.027	9	view →
CCRCC	DFS	Median	III,IV	0.580	0.835	.017	7	view →
UCEC	OS	Median	II,III,IV	0.666	1.000	.025	4	view →
LUAD	DFS	Median	All	0.885	1.000	.009	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

PTTG1IP–COAD (DFS)

Open the COAD breakdown →