PTTG1IP

Across TCGA patient cohorts, PTTG1IP RNA expression is significantly associated with the protein abundance of many other proteins, with 11,447 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PTTG1IP-associated proteins across cancer lineages are PLEC, PALLD, and PTCD3. Each is linked with PTTG1IP in more than 5 cancer types. Because this analysis shows association rather than direction, both PTTG1IP-to-partner and partner-to-PTTG1IP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTTG1IP versus PLEC in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTTG1IP→partner) and Y-score (partner→PTTG1IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLEC →	+0.433	+0.373	<.001	.002	3	6
LSCC	PALLD →	+0.529	+0.360	<.001	.001	3	6
COAD	PTCD3 →	-0.342	-0.494	<.001	<.001	3	5
BRCA	PXN →	+0.237	+0.396	<.001	<.001	3	5
BRCA	RAI14 →	+0.472	+0.513	<.001	<.001	3	5
BRCA	FLNA_S1459 →	+0.655	+0.511	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,447 associations by consensus.

PTTG1IP vs PLEC — GBM

Explore this scatter interactively →