PTTG1IP

Across TCGA patient cohorts, PTTG1IP protein abundance is significantly associated with the RNA expression of many other genes, with 7,619 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible PTTG1IP-associated genes across cancer lineages are ODC1, LY6E, and SLC50A1. Each is linked with PTTG1IP in more than 3 cancer types. Because this analysis shows association rather than direction, both PTTG1IP-to-partner and partner-to-PTTG1IP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTTG1IP versus ODC1 in HNSC, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTTG1IP→partner) and Y-score (partner→PTTG1IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ODC1 →	-1.502	-0.248	<.001	<.001	3	4
COAD	LY6E →	+1.081	+0.551	<.001	.001	3	3
OV	SLC50A1 →	+0.423	+0.535	.001	.005	3	3
OV	SUMO3 →	+0.412	+0.634	.002	<.001	3	3
HNSC	SGIP1 →	+0.598	+0.186	<.001	.009	3	3
LSCC	EPS8L1 →	+0.874	+0.283	.003	.001	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,619 associations by consensus.

PTTG1IP vs ODC1 — HNSC

Explore this scatter interactively →