PTTG1

Across TCGA patient cohorts, PTTG1 protein abundance is significantly associated with the RNA expression of many other genes, with 928 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible PTTG1-associated genes across cancer lineages are EIF3D, RANGAP1, and PLEKHJ1. Each is linked with PTTG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both PTTG1-to-partner and partner-to-PTTG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTTG1 versus EIF3D in HNSC, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTTG1→partner) and Y-score (partner→PTTG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	EIF3D →	+1.486	+0.556	.004	.004	3	2
HNSC	RANGAP1 →	+1.294	+0.519	.004	.009	3	2
HNSC	PLEKHJ1 →	+1.126	+0.570	.003	.003	3	2
HNSC	TPI1 →	+2.200	+0.556	.003	.004	3	2
HNSC	ETF1 →	+0.977	+0.621	.006	<.001	3	2
HNSC	RPL36 →	+2.285	+0.559	.002	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 928 associations by consensus.

PTTG1 vs EIF3D — HNSC

Explore this scatter interactively →