PTRH2

Across TCGA patient cohorts, PTRH2 protein abundance is significantly associated with the RNA expression of many other genes, with 12,994 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTRH2-associated genes across cancer lineages are JAK1, RAPGEF3, and NFKB1. Each is linked with PTRH2 in more than 5 cancer types. Because this analysis shows association rather than direction, both PTRH2-to-partner and partner-to-PTRH2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTRH2 versus JAK1 in HNSC, with a Pearson correlation of -0.22.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTRH2→partner) and Y-score (partner→PTRH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	JAK1 →	-0.415	-0.292	.004	.001	3	6
CCRCC	RAPGEF3 →	-0.724	-0.260	<.001	.003	3	6
UCEC	NFKB1 →	-0.527	-0.528	<.001	.001	3	5
BRCA	TUBD1 →	+0.626	+0.630	<.001	<.001	3	5
LSCC	CNRIP1 →	-0.557	-0.350	<.001	<.001	3	5
OV	ZBTB46 →	-0.647	-0.291	.005	.006	2	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,994 associations by consensus.

PTRH2 vs JAK1 — HNSC

Explore this scatter interactively →