PTRH2

Across TCGA cell cohorts, PTRH2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,082 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PTRH2-associated GO terms across cancer lineages are Positive regulation of anoikis, tRNA C3-cytosine methylation, and Positive regulation of mitochondrial translation. Each is linked with PTRH2 in more than 12 cancer types. Because this analysis shows association rather than direction, both PTRH2-to-partner and partner-to-PTRH2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of anoikis grouped by PTRH2-low versus PTRH2-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTRH2→partner) and Y-score (partner→PTRH2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Positive regulation of anoikis →	+0.198	+0.936	<.001	<.001	3	13
LUNG_SCLC	tRNA C3-cytosine methylation →	+0.160	+0.673	<.001	<.001	3	11
LUNG_SCLC	Positive regulation of mitochondrial translation →	+0.152	+0.529	<.001	<.001	3	11
LUNG_SCLC	Maturation of 5.8S rRNA →	+0.117	+0.721	.001	<.001	3	11
LUNG_SCLC	rRNA processing →	+0.137	+0.834	<.001	<.001	3	11
LUNG_SCLC	tRNA modification →	+0.051	+0.569	<.001	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,082 associations by consensus.

Positive regulation of anoikis by PTRH2 expression — OVARY

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