PTPRZ1

Across TCGA patient cohorts, PTPRZ1 protein abundance is significantly associated with the RNA expression of many other genes, with 9,187 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTPRZ1-associated genes across cancer lineages are CYP2C18, GPRC5D, and BATF3. Each is linked with PTPRZ1 in more than 2 cancer types. Because this analysis shows association rather than direction, both PTPRZ1-to-partner and partner-to-PTPRZ1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPRZ1 versus CYP2C18 in LUAD, with a Pearson correlation of 0.25.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPRZ1→partner) and Y-score (partner→PTPRZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CYP2C18 →	+1.210	+0.910	<.001	.001	3	3
HNSC	GPRC5D →	+1.020	+0.559	<.001	<.001	3	3
HNSC	BATF3 →	-0.729	-0.585	<.001	<.001	3	3
LSCC	FAM83C →	+1.642	+0.941	<.001	<.001	3	3
HNSC	SLC8A1 →	-0.615	-0.442	<.001	<.001	3	3
HNSC	GPRIN3 →	-0.871	-0.581	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,187 associations by consensus.

PTPRZ1 vs CYP2C18 — LUAD

Explore this scatter interactively →