PTPRQ

Across TCGA patient cohorts, PTPRQ RNA expression is significantly associated with the go_rna of many other GO terms, with 7,112 significant associations in total. STAD shows the largest number of these associations.

The most reproducible PTPRQ-associated GO terms across cancer lineages are Regulation of protein polymerization, Regulation of endocytosis, and Positive regulation of protein-containing complex assembly. Each is linked with PTPRQ in more than 20 cancer types. Because this analysis shows association rather than direction, both PTPRQ-to-partner and partner-to-PTPRQ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein polymerization grouped by PTPRQ-low versus PTPRQ-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPRQ→partner) and Y-score (partner→PTPRQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein polymerization →	+0.076	+0.084	<.001	<.001	3	21
STAD	Regulation of endocytosis →	+0.067	+0.113	<.001	<.001	3	20
STAD	Positive regulation of protein-containing complex assembly →	+0.080	+0.080	<.001	<.001	3	20
STAD	Regulation of macroautophagy →	+0.087	+0.077	<.001	<.001	3	20
STAD	Cytoskeleton-dependent intracellular transport →	+0.056	+0.072	<.001	<.001	3	20
STAD	Actomyosin structure organization →	+0.072	+0.109	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,112 associations by consensus.

Regulation of protein polymerization by PTPRQ expression — STAD

Explore this box plot interactively →