PTPRN2

Across TCGA cell cohorts, PTPRN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,242 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible PTPRN2-associated GO terms across cancer lineages are Mitochondrial electron transport, cytochrome c to oxygen, Vesicle docking, and Establishment of vesicle localization. Each is linked with PTPRN2 in more than 7 cancer types. Because this analysis shows association rather than direction, both PTPRN2-to-partner and partner-to-PTPRN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial electron transport, cytochrome c to oxygen grouped by PTPRN2-low versus PTPRN2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPRN2→partner) and Y-score (partner→PTPRN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Mitochondrial electron transport, cytochrome c to oxygen →	+0.077	+2.291	.001	<.001	3	8
LUNG_SCLC	Vesicle docking →	+0.063	+2.073	.006	.003	3	7
LUNG_SCLC	Establishment of vesicle localization →	+0.065	+2.938	<.001	<.001	3	7
BLOOD_Leukemia	Tear secretion →	-0.700	-1.189	.003	.001	3	7
LUNG_SCLC	Organelle localization by membrane tethering →	+0.040	+1.634	.004	.002	3	6
LUNG_SCLC	Membrane docking →	+0.044	+2.441	.004	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,242 associations by consensus.

Mitochondrial electron transport, cytochrome c to oxygen by PTPRN2 expression — LUNG_SCLC

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