PTPRH

Across TCGA cell cohorts, PTPRH RNA expression is significantly associated with the go_rna of many other GO terms, with 4,949 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible PTPRH-associated GO terms across cancer lineages are Negative regulation of MAPK cascade, Regulation of double-strand break repair via homologous recombination, and Regulation of muscle adaptation. Each is linked with PTPRH in more than 9 cancer types. Because this analysis shows association rather than direction, both PTPRH-to-partner and partner-to-PTPRH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of MAPK cascade grouped by PTPRH-low versus PTPRH-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPRH→partner) and Y-score (partner→PTPRH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Negative regulation of MAPK cascade →	+0.063	+1.639	<.001	<.001	3	10
LIVER	Regulation of double-strand break repair via homologous recombination →	-0.086	-1.831	.008	.003	3	10
PANCREAS	Regulation of muscle adaptation →	+0.107	+1.989	<.001	<.001	3	10
PANCREAS	Regulation of alpha-beta T cell proliferation →	+0.171	+1.450	.001	.006	3	10
PANCREAS	Regulation of muscle system process →	+0.055	+1.260	<.001	<.001	3	10
STOMACH	GDF15-GFRAL signaling pathway →	+1.238	+1.713	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,949 associations by consensus.

Negative regulation of MAPK cascade by PTPRH expression — PANCREAS

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