Q-omics provides the consensus-scored PTPRD-AS1 profile across patient tissues and cancer cell-line models. PTPRD-AS1 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in ESCA. Among the 18 cancer types available for tumor–normal comparison, PTPRD-AS1 is differentially expressed in 13, with the highest sampling consensus in LUAD. Additionally, PTPRD-AS1 RNA expression shows 18,501 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight ESCA, LUAD, and GBM as cancer lineages where PTPRD-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for PTPRD-AS1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes PTPRD-AS1 survival associations across molecular data types. PTPRD-AS1 RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible PTPRD-AS1 RNA expression–survival associations across cancer types. High PTPRD-AS1 expression shows unfavorable associations in OV, BLCA and ACC, but favorable associations in ESCA, UCS and COAD. The ESCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify ESCA as the clearest survival context for PTPRD-AS1 RNA expression.
This table summarizes PTPRD-AS1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in LUAD for RNA.
This table ranks reproducible tumor–normal expression differences for PTPRD-AS1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. PTPRD-AS1 shows lower tumor expression in LUAD, BLCA, THCA, KICH, UCEC and LUSC. The LUAD box plot shows higher PTPRD-AS1 RNA expression in normal versus tumor tissue (log2 FC = −1.137, t-test p < 0.001).
This table shows molecular features associated with PTPRD-AS1 in patient tissues and cancer cell lines. In patient samples, PTPRD-AS1 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
