PTPN3

Across TCGA patient cohorts, PTPN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,625 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTPN3-associated proteins across cancer lineages are PTPN3_S359, CORO2A, and PTPN3_S372. Each is linked with PTPN3 in more than 8 cancer types. Because this analysis shows association rather than direction, both PTPN3-to-partner and partner-to-PTPN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPN3 versus PTPN3_S359 in OV, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPN3→partner) and Y-score (partner→PTPN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PTPN3_S359 →	+0.945	+1.084	<.001	<.001	3	9
UCEC	CORO2A →	+0.642	+0.893	<.001	<.001	3	7
GBM	PTPN3_S372 →	+0.849	+1.783	.005	.003	3	7
COAD	WDR5 →	+0.295	+0.640	<.001	<.001	3	6
HNSC	STRBP →	+0.604	+0.718	<.001	<.001	3	6
HNSC	FAM120A →	+0.161	+0.685	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,625 associations by consensus.

PTPN3 vs PTPN3_S359 — OV

Explore this scatter interactively →