PTPN13

Across TCGA cell cohorts, PTPN13 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,335 significant associations in total. BONE shows the largest number of these associations.

The most reproducible PTPN13-associated GO terms across cancer lineages are Nuclear export, Schwann cell differentiation, and Viral translational termination-reinitiation. Each is linked with PTPN13 in more than 9 cancer types. Because this analysis shows association rather than direction, both PTPN13-to-partner and partner-to-PTPN13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear export grouped by PTPN13-low versus PTPN13-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPN13→partner) and Y-score (partner→PTPN13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Nuclear export →	+0.075	+0.948	<.001	.006	2	10
UPPER_AERODIGESTIVE_TRACT	Schwann cell differentiation →	+0.104	+1.227	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.078	+0.958	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Negative regulation of chromosome condensation →	+0.124	+1.049	.009	.004	3	8
UPPER_AERODIGESTIVE_TRACT	Schwann cell development →	+0.098	+1.101	<.001	.002	3	8
OESOPHAGUS	Nucleocytoplasmic transport →	+0.088	+2.400	.008	.005	2	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,335 associations by consensus.

Nuclear export by PTPN13 expression — SKIN

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