PTPN12

Across TCGA patient cohorts, PTPN12 RNA expression is significantly associated with the RNA expression of many other genes, with 20,744 significant associations in total. ACC shows the largest number of these associations.

The most reproducible PTPN12-associated genes across cancer lineages are DNAJC13, IQGAP1, and NPAT. Each is linked with PTPN12 in more than 33 cancer types. Because this analysis shows association rather than direction, both PTPN12-to-partner and partner-to-PTPN12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPN12 versus DNAJC13 in UVM, with a Pearson correlation of 0.80.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPN12→partner) and Y-score (partner→PTPN12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	DNAJC13 →	+1.629	+1.116	<.001	<.001	3	34
UVM	IQGAP1 →	+1.750	+1.430	<.001	<.001	3	34
UVM	NPAT →	+1.324	+1.628	<.001	<.001	3	34
THYM	ADAM17 →	+1.846	+1.177	<.001	<.001	3	34
UVM	TMEM87B →	+1.373	+1.495	<.001	<.001	3	34
UVM	NCBP1 →	+1.131	+1.538	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,744 associations by consensus.

PTPN12 vs DNAJC13 — UVM

Explore this scatter interactively →