PTPMT1

Across TCGA patient cohorts, PTPMT1 protein abundance is significantly associated with the protein abundance of many other proteins, with 11,731 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible PTPMT1-associated proteins across cancer lineages are MRPL24, TIMM44, and LARS2. Each is linked with PTPMT1 in more than 7 cancer types. Because this analysis shows association rather than direction, both PTPMT1-to-partner and partner-to-PTPMT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPMT1 versus MRPL24 in COAD, with a Pearson correlation of 0.37.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPMT1→partner) and Y-score (partner→PTPMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MRPL24 →	+0.319	+0.349	<.001	.001	3	8
CCRCC	TIMM44 →	+0.427	+0.318	<.001	<.001	3	8
UCEC	LARS2 →	+0.447	+0.603	<.001	<.001	3	8
LUAD	MRPL45 →	+0.375	+0.429	<.001	<.001	3	7
UCEC	MTCH2 →	+0.529	+0.472	.001	.003	2	8
BRCA	TAMM41 →	+0.496	+0.427	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,731 associations by consensus.

PTPMT1 vs MRPL24 — COAD

Explore this scatter interactively →