PTPA

Across TCGA patient cohorts, PTPA RNA expression is significantly associated with the protein abundance of many other proteins, with 8,320 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible PTPA-associated proteins across cancer lineages are LRSAM1, SSNA1, and PRRC2B. Each is linked with PTPA in more than 5 cancer types. Because this analysis shows association rather than direction, both PTPA-to-partner and partner-to-PTPA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPA versus LRSAM1 in OV, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPA→partner) and Y-score (partner→PTPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LRSAM1 →	+0.222	+0.517	.004	.002	3	6
COAD	SSNA1 →	+0.643	+0.608	<.001	<.001	3	6
LSCC	PRRC2B →	+0.347	+0.443	<.001	<.001	3	5
BRCA	RAB14 →	+0.321	+0.575	<.001	.001	3	5
OV	SET →	+0.390	+0.530	.001	.001	3	5
OV	NTMT1 →	+0.391	+0.573	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,320 associations by consensus.

PTPA vs LRSAM1 — OV

Explore this scatter interactively →