PTPA

Across TCGA patient cohorts, PTPA protein abundance is significantly associated with the RNA expression of many other genes, with 20,249 significant associations in total. GBM shows the largest number of these associations.

The most reproducible PTPA-associated genes across cancer lineages are TBC1D13, USP20, and ALAD. Each is linked with PTPA in more than 7 cancer types. Because this analysis shows association rather than direction, both PTPA-to-partner and partner-to-PTPA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, PTPA versus TBC1D13 in OV, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPA→partner) and Y-score (partner→PTPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TBC1D13 →	+0.535	+0.400	.008	.008	3	7
OV	USP20 →	+0.863	+0.665	.001	.001	2	8
BRCA	ALAD →	+0.737	+0.330	<.001	<.001	3	7
BRCA	LINC00963 →	+0.547	+0.260	<.001	<.001	3	7
OV	TSC1 →	+0.875	+0.481	<.001	.001	3	7
OV	COQ4 →	+0.964	+0.806	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,249 associations by consensus.

PTPA vs TBC1D13 — OV

Explore this scatter interactively →