PTPA

Across TCGA cell cohorts, PTPA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,173 significant associations in total. CNS shows the largest number of these associations.

The most reproducible PTPA-associated GO terms across cancer lineages are CTP salvage, Response to oscillatory fluid shear stress, and Cellular response to oscillatory fluid shear stress. Each is linked with PTPA in more than 9 cancer types. Because this analysis shows association rather than direction, both PTPA-to-partner and partner-to-PTPA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CTP salvage grouped by PTPA-low versus PTPA-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (PTPA→partner) and Y-score (partner→PTPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	CTP salvage →	+0.119	+0.733	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Response to oscillatory fluid shear stress →	+0.147	+0.663	.002	.002	3	10
LUNG_NSCLC_LUSC	Cellular response to oscillatory fluid shear stress →	+0.147	+0.663	.002	.002	3	10
LUNG_NSCLC_LUSC	Vascular endothelial cell response to oscillatory fluid shear stress →	+0.147	+0.663	.002	.002	3	10
UPPER_AERODIGESTIVE_TRACT	Response to platinum ion →	+0.138	+0.828	.001	.001	3	9
LARGE_INTESTINE	Regulation of chromatin organization →	+0.062	+0.433	<.001	.006	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,173 associations by consensus.

CTP salvage by PTPA expression — URINARY_TRACT

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